Department of Probability and Statistics

MAS461/MAS361 Medical Statistics

Material relating to MAS461/MAS361 Medical Statistics is available from this course web page. This course was previously designated PAS461/PAS36. Material for the parallel course MAS6012 is available via the University's Blackboard (MOLE) system. Lecture notes etc are in .pdf form and may be read and printed with Adobe Acrobat. The data sets are in R, Minitab, SPSS, SAS or S-plus form as indicated. It is recommended that you use Microsoft Internet Explorer (and not Netscape) to access these, clicking on them gives the option of downloading or running from the web sources. Downloading is recommended and is necessary for the R data sets.

The computer package for the course is R. A brief introduction to R is given here. More information is given on the CRAN home page.

Corrections and Clarifications
[updated 11/11/11]

Lecture notes:

Study Guide for Medical Statistics

Syllabus for MAS361 (Medical Statistics)
Syllabus for MAS461 (Medical Statistics)

Syllabus for MAS6012 (Medical Statistics, Sampling Theory and Design of Experiments)

Clinical Trials: Lecture Notes, one page to the sheet version (1.1MB)
Survival Analysis: Lecture Notes, one page to the sheet version (1.0MB)

Click here for links to lecture podcasts, vodcasts and rich media recordings of lectures.

The lecture notes are given in a complete Acrobat .pdf file with a hot-linked table of contents immediately following the title page.
To print just one of the chapters note that the printed pages numbers in the contents list and in the notes do not correspond with those of the .pdf file. Instead, use the contents list to move to the start of the chapter and note the page number given at the bottom of the Acrobat window. This will allow you to issue a print instruction for the appropriate number of pages starting at that point.

Clinical Trials: Lecture Slides, Sections 0 to 2
Clinical Trials: Lecture Slides, Sections 3 to 4
Clinical Trials: Lecture Slides, Section 5
Clinical Trials: Lecture Slides, Section 6
Clinical Trials: Lecture Slides, Section 7
Clinical Trials: Lecture Slides, Section 8
Clinical Trials: Lecture Slides, Section 9
Clinical Trials: Lecture Slides, Section 10

Survival Analysis: Lecture Slides, Sections 0 to 2.5
Survival Analysis: Lecture Slides, Sections 2.6 to 2.7
Survival Analysis: Lecture Slides, Chapter 3
Survival Analysis: Lecture Slides, Chapter 4

Additional Informal Lecture notes:

Sample size tips

Neave's table tips

Revision of hypothesis tests

Weekly Tasks and Exercises:

Clinical Trials Tasks for Week 1
Clinical Trials Tasks for Week 2
Clinical Trials Tasks for Week 3
Clinical Trials Tasks for Week 4
Clinical Trials Tasks for Week 5

Survival Analysis Tasks for Week 6
Survival Analysis Tasks for Week 8
Survival Analysis Tasks for Week 9
Survival Analysis Tasks for Week 10
Survival Analysis Tasks for Week 11

Medical Statistics Exercises 1
Medical Statistics Exercises 2
Medical Statistics Exercises 3

Solutions to task sheets:

Task sheets are intended for self-assessment of understanding of course material.
Outline solutions will only be provided three to four weeks after the
relevent material has been covered in lectures (see Study Guide).
This is to allow plenty of time to go back to check the relevant sections
of the lecture notes & slides if you cannot see immediately how to do the tasks.

Weekly Tasks (Clinical Trials): Solutions to Weeks 1-3

Weekly Tasks (Clinical Trials): Solutions to Weeks 4 & 5

Weekly Tasks (Survival Analysis): Solutions to Weeks 6-9

Weekly Tasks (Survival Analysis): Solutions to Weeks 10-11

Solutions to Exercises:

Solutions to exercises will be provided shortly after the submission date.

Solutions to Medical Statistics Exercises 1 Feedback on Exercises 1

Solutions to Medical Statistics Exercises 2 Feedback on Exercises 2

Solutions to Medical Statistics Exercises 3 Feedback on Exercises 3

Guide to Course Work Grading

R Script Files for Task Sheets and Exercises etc:

Past Exam Papers

Copies of previous exam papers are available here.

Rubric and Allowed material in open book examinations

The rubric on the examination papers is
RESTRICTED OPEN BOOK EXAMINATION.
Candidates may bring to the examination lecture notes and associated lecture material (but no textbooks) plus a calculator that conforms to University regulations. All answers will be marked but credit will be given for only the best THREE answers.
All questions carry equal marks. Total marks 99.
(NB: The total marks in the case of the PAS461 examination is 75).
Definition of "lecture notes and associated lecture material": This consists of anything that you have downloaded and printed from this course page, including example sheets and solutions, examination papers and solutions to the past two years' of examination papers (i.e. for 2009/10 and 2010/11 ONLY) together with any personal notes you have made and any annotations you have personally made on material printed from this course page and any material distributed in the MAS361/461 lectures. It does not include any material printed from other module pages nor any examination papers and solutions for years other than the previous two years nor any text books (even if listed as recommended texts within the course material).

Solutions to past exam papers:

Solutions to PAS361, 2009/10, are available here
Solutions to PAS461, 2009/10, are available here
Solutions to MAS361, 2010/11, are available here
Solutions to MAS461, 2010/11, are available here

Brian Everitt's Data Sets and Functions:

Click here to access Brian Everitt's webpage containing functions and data sets
from his book (with Sophie Rabe-Hesketh) Analyzing Medical Data Using S-PLUS.